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Apart from simple sequencing and looping, radare2 allows to write simple macros, using this construction:

[0x00404800]> (qwe, pd 4, ao)

This will define a macro called 'qwe' which runs sequentially first 'pd 4' then 'ao'. Calling the macro using syntax .(macro) is simple:

[0x00404800]> (qwe, pd 4, ao)
[0x00404800]> .(qwe)
0x00404800  mov eax, 0x61e627      ; "tab"
0x00404805  push rbp
0x00404806  sub rax, section_end.LOAD1
0x0040480c  mov rbp, rsp

address: 0x404800
opcode: mov eax, 0x61e627
prefix: 0
bytes: b827e66100
ptr: 0x0061e627
refptr: 0
size: 5
type: mov
esil: 6415911,rax,=
stack: null
family: cpu
[0x00404800]>

To list available macroses simply call (*:

[0x00404800]> (*
(qwe , pd 4, ao)

And if want to remove some macro, just add '-' before the name:

[0x00404800]> (-qwe)
Macro 'qwe' removed.
[0x00404800]>

Moreover, it's possible to create a macro that takes arguments, which comes in handy in some simple scripting situations. To create a macro that takes arguments you simply add them to macro definition. Be sure, if you're using characters like ';', to quote the whole command for proper parsing.

[0x00404800]
[0x004047d0]> "(foo x y,pd $0; s +$1)"
[0x004047d0]> .(foo 5 6)
;-- entry0:
0x004047d0      xor ebp, ebp
0x004047d2      mov r9, rdx
0x004047d5      pop rsi
0x004047d6    mov rdx, rsp
0x004047d9    and rsp, 0xfffffffffffffff0
[0x004047d6]>

As you can see, the arguments are named by index, starting from 0: $0, $1, ...